SISCOM
SISCOM is an acronym for “Subtraction Ictal-Interictal SPECT co-registered to MRI”. It is an imaging done in patients with refractory epilepsy planned for surgery.
SISCOM
How Is Siscom Done?
SISCOM requires the acquisition of 3 scans, which are an MRI scan, an ictal SPECT scan and interictal SPECT scan.
An interictal SPECT scan involves injection of a radiotracer that gives information about the blood flow to the brain. An image is acquired using a gamma camera 1-4 hours after injection when the patient is seizure free.
An ictal SPECT involves injection of the same radiotracer as an interictal SPECT with the difference that the injection is done when the patient is having a seizure.
Together, these three images are processed in a computer and the resultant findings can help localize the possible source of epilepsy in the patient.